Antha (Synthace)

Antha from Synthace is a software-first platform designed to help discovery biology teams design, run and scale complex experiments more reliably and faster. It targets workflows that traditionally require many one-off experiments and manual steps—assay development, construct assembly, purification process development and lead discovery—by combining principled experimental design with automation and operational structure. The platform is delivered with hands-on expertise: Synthace’s specialists help teams adopt multivariate methods and automation practices so scientific questions can be explored with fewer experiments and clearer outcomes. At its core, Antha supports multifactorial experimental design (DOE) and automation of lab protocols so labs can move from manual, hard-to-reproduce procedures to machine-executable workflows. The software lets users specify high-level experimental intent—variables, constraints and measurements—then translates that intent into deterministic steps for liquid handlers, dispensers and other lab equipment. That approach enforces standardized experimental structure across teams, reduces manual errors, and creates outputs that support robust go / no‑go decisions. Customers report substantial performance gains: examples include more than a tenfold increase in experimental throughput and routine execution of dozens of constructs or conditions that previously required heavy manual effort. Typical use cases include assay optimization (reducing the number of runs required to find robust conditions), purification process development using DOE, accelerating construct build-test cycles, and standardizing workflows for high-content and high-throughput screening campaigns. Synthace emphasizes practical delivery: teams commonly start with a few high-impact pilot projects delivered by Synthace specialists, who work alongside in-house scientists to tune experimental designs and automation logic. This hands-on model shortens time-to-value because it leverages existing lab personnel and instrumentation rather than requiring a wholesale change to hardware or processes. Integration and adoption are treated as part of the offering. Synthace positions its specialists as extensions of client teams, providing on-site training, protocol design help, and scaling guidance so groups become self-sufficient over time. The platform is designed to work with the dispensers and automation hardware already present in the lab from day one, which reduces setup friction and lets teams realize benefits quickly. By combining software, trained staff, and a standardized approach to experimentation, Antha helps organizations turn complex, variable-rich biology experiments into reproducible, high-throughput workflows that generate reliable data for faster decision-making.